Welcoming Dr. Adélaïde Doussau!
Dr. Adélaïde Doussau is an MD with a PhD in public health, epidemiology, and clinical trial design, with an interest in providing researchers with methodological support in study design, and ethics. She has an extensive background in clinical research methodology. As an Assistant Professor at the Bordeaux Clinical Trial Unit (France), she taught trial methods, provided consultations to clinicians conducting epidemiologic studies, supervised statisticians and data managers, and developed her own research on dose-finding designs in oncology trials.
As a methodologist, Dr. Dousau contributed to over 20 studies funded through hospital or national competitive academic grants. Many studies were trials, although she has also contributed to prognostic cohorts, diagnostic, and case-control studies.
She worked on various fields, including oncology, pediatrics, geriatrics, infectious disease and surgery. Her role in her various co-authorships includes recommending designs, revising protocols before submission for grant funding or ethics review, collaborating on the construction of case report forms (CRF) and databases, overseeing the data-management and statistical analysis plans, performing statistical analyses (e.g. survival analysis, logistic models, mixed models), interpreting results, and contributing to publication or dissemination of findings in scientific conferences.
Dr. Doussau has advanced training in research ethics consultation, and research ethics committee review, with two postdoctoral fellowships: in the Department of Bioethics at the NIH and in McGill`s Biomedical Ethics Unit. She has been serving on the Doctor Without Borders (MSF) research ethics committee since 2017.
She has joined St Mary’s Research Center as Project Development and Consultation Coordinator at the beginning October. She is a key part of the core support provided by the Research Center to to strengthen research capacity in St Mary`s Hospital staff. The support that she can provide includes helping staff and researchers with study design of research grant applications and research protocols (such as defining objectives, methods, sample size considerations), implementation (such as support in the design of questionnaires) and contribution in the interpretation of results.
Selected publications of the past 5 years
- Doussau A, Vinarov E, Barsanti-Ines B, Kimmelman J. Comparison Between Protocols and Publications for Prognostic and Predictive Cancer Biomarker Studies. Clinical Trials 2019 - Accepted.
- Hutchinson N, Capron A, Doussau A. Research Participants Should Have the Option to Be Notified of Results of Unknown but Potential Significance. Am J Bioeth. 201
- Hemming K, M Taljaard, JE McKenzie, A Doussau, […], S Eldridge, MJ Campbell, RJ Lilford, C Weijer, A Forbes, JM Grimshaw. Reporting of Stepped-Wedge Cluster Randomised Trials: Extension of the CONSORT 2010 statement with explanation and elaboration. BMJ. 2018
- Rullier E, Rouanet P, Tuech JJ, […], Asselineau J, Doussau A. Organ Preservation for Rectal Cancer: the GRECCAR 2 randomized phase 3 trial. The Lancet, 2017
- Hemming K, M Taljaard, JE McKenzie, A Doussau, […], S.E
- McCormick JB, Wu JT, Doussau A. Is it ethically acceptable to screen patients for obstructive sleep apnea and not offer them Positive Air Pressure therapy in a clinical trial? Am J Bioeth. 2017.
- Doussau A, Hanmer C. A rationale for relaxing the requirement to undergo a non-curative chemotherapy for advanced cancer in a phase I immunotherapy trial. Am J Bioeth. 2017.
- Doussau A, Grady C. The ethics of studying financial incentives in public health implementation. Am J Bioeth. 2016.
- Doussau A, Grady C. Deciphering assumptions about Stepped Wedge Designs: The case of Ebola vaccine research. J. of Medical Ethics, 2016.
- Doussau A, Geoerger B, Jiménez I, Paoletti X. Innovations for phase I dose-finding designs in pediatric oncology clinical trials. Contemp Clin Trials 2016.
- Bourdel-Marchasson I, Diallo A, Bellera C, […] Mathoulin-Pélissier S, Soubeyran P, Rainfray M, Fonck M, Doussau A. One-year mortality in older patients with cancer: development and external validation of an MNA-based prognostic score. PlosOne 2016; 9;11(2).
- Doussau A, Thiébaut R, Geoerger B, Schöffski P, Floquet A, Le Deley MC, Mathoulin-Pélissier S, Rizzo E, Fumoleau P, Le Tourneau C, Paoletti X. A new approach to integrate toxicity grade and repeated treatment cycles in the analysis and reporting of phase I dose-finding trials. Ann Oncol. 2015.
- Pereira B, Doussau A, Mathoulin-Pélissier S. Mise en œuvre d'un essai clinique de phase II. In: John Libbey Eurotext, editor. Méthodes biostatistiques appliquées à la recherche clinique en cancérologie. Montrouge 2011. P. 281-300.
Caregivers and mental health
Dr, Jeannie Haggerty resigned as Scientific director of the McGill Réseau-1-Québec
Dr. Haggerty resigned from her position as Scientific Director of Réseau-1 Québec. The new Scientific Director of Réseau-1 Québec, Yves Couturier is from the Université de Sherbrooke (Campus of Longueuil).
Congratulation to Dr. Sylvie Lambert for her Canada Research Chairs
On Friday, Dec. 2, Kirsty Duncan, Minister of Science, announced over $173 million in funding for 203 Canada Research Chairs (CRC) at universities across Canada. Sixteen CRCs went to McGill. CRCs are granted to outstanding researchers acknowledged by their peers as world leaders in their fields.
Join me to congratulate Dr. Sylvie Lambert, Assistant Professor of Nursing – Tier 2 – for her Canada Research Chair in Sustainable Self-Management Support for Patients with Cancer and Their Family Caregivers. Tier 2 Chairs, valued at $100,000 annually for five years.
More details coming soon
Congratulation to Dr. Sylvie Lambert and her collaborators for their grants :
''Adapting a self-directed coping skills intervention for caregivers of patients with advanced cancer: '' funded from Réseau de recherché en interventions en sciences infirmières du Québec (RRISIQ) FRQS-MSS.
'' Older adults with a chronic physical condition and comorbid depression and their family caregivers: Partners in the co-design of a dyadic self-care depression intervention '' funded from Drummond Foundation.
Congratulation to Dr. Susan Law and her collaborators for her grant from the Ontario SPOR SUPPORT Unit in the Patient-Oriented Research Capacity Building Initiatives Awards competition.
Dr, Jeannie Haggerty appointed as Scientific director of the McGill Réseaux de recherche axée sur les pratiques de première ligne
Dr. Haggerty accepted the position of Scientific Director of McGill's RRAPPL (Networks of Research Focused on Primary Practices), which is also part of Réseau-1 Québec.
Dr, Jeannie Haggerty resigned as Scientific director of the McGill Réseau-1-Québec
Dr. Haggerty resigned from her position as Scientific Director of Réseau-1 Québec. Shandi Miller and Danielle Shrimer will transfer to Longueuil on December 22 to work with the new Scientific Director of Réseau-1 Québec, Yves Couturier at the Université de Sherbrooke. (Longuueil)
Appointment of Dr. Jeannie Haggerty as interim Scientific Director of St. Mary's Research Centre
Congratulation to Dr. Jeannie Haggerty for her appointment that was announced on October 18th.
Healthexperience.ca website official launch
The healthexperiences.ca website was launched at a special event organized by Dr Susan Law and her team on October 19th. Thirty-five people (patients, professionals, community organizations and researchers) were in attendance. The website is a collection of the experiences of caregivers and the experiences of women with breast cancer. It is now available in English. The French version of the website will be published on www.experiencessante.ca in early spring 2017. Congratulation to the Tearn !
Welcome to Emily Pye and Courtney Abbott 2 students from the The Atlantic Regional Training Centre (ARTC)
Read the messages from Emily Pye and Courtney Abbott to learn more about them and their projects at St. Mary's :
I am currently doing my master’s in Applied Health Services Research at Memorial University of Newfoundland, and conducting research for my thesis concerning medical students’ perceptions of their writing competencies.
This summer, I am involved with three major projects ongoing at the research centre with Dr. Susan Law and Michel Lortie. Firstly, I will be helping with the Breast Cancer Health Experiences project, aiding in the preparation of a manuscript for publication (Law). Secondly, I will be involved in the recruitment process and collection of data for the clinical study of the comfort, unobtrusiveness, and irritation potential of biometric sensors on human skin (Law and Lortie). Lastly, I will be visiting the maternity ward to distribute surveys to new mothers to evaluate the new quiet time policy (Law).
I look forward to getting to know everyone over the summer!
I am completing a Master of Science in Medicine (Applied Health Services Research) at Memorial University. My project is titled "Long-term food insecurity and obesity in Newfoundland and Labrador (NL)." Previous research has shown that food insecurity is positively correlated with obesity throughout Canada as a whole. Newfoundland and Labrador, however, has the lowest rate of food insecurity but the highest rate of obesity out of any of the Canadian provinces, contradicting previous findings. My project involves data analysis of the Statistics Canada National Population Health Survey (NPHS) to assess what factors are involved in this interesting relationship.
This summer I'll be helping Susan Law's research team with a number of different projects, including the Health Experiences website, the Caregiving module, as well as the Quiet Time Project evaluation.
Congratulation to Dr. Susan Law and Dr. Donna Tataryn for the awarded grant from Quebec Breast Cancer Foundation
During the Quebec Breast Cancer Foundation gala on May 3rd, the results of the second edition of its province-wide 1 Million to Help Contest were revealed. We are proud to announce that Dr. Susan Law and Dr. Donna Tataryn were awarded a grant for the project: Behind every surgery, there’s a story - women sharing their experiences to help others prepare for breast surgery in the amount of 156 732$.
Quebec Breast Cancer Foundation announcement http://www.rubanrose.org/Concours_1_million_pour_aider-fr-289
Congratulation to Dr. Jeannie Haggerty on her appointment as Full Professor at Mcgill University
Please join me in congratulating Dr Jeannie Haggerty on her appointment on May 2, 2016 as full professor at McGill University.
She holds the first McGill Chair in Family and Community Medicine Research, based at St. Mary’s Hospital Centre and McGill University, and she is the Scientific Director of the Réseau de connassances en soins intégrés de premier ligne du Québec.
2016 C.A.R.E. Grants awarded researchers
St. Mary's Research Centre has awarded 3 C.A.R.E. Grants in 2016 :
Dr. Rick Mah and his team for the project entitled ''Improving intubation through video reflexive ethnography: Towards a culture of collaborative learning givers'' ($ 19,800)
Dr. Sylvie Lambert and her team for the project entitled ''A mixed methods pilot study of the illness self-management skills, needs, barriers, and preferences for interventions among patients from a culturally and linguistically diverse (CALD) background and their family caregivers ''($ 20,000)
Dr. Susan Law and her team for the project entitled ''Introducing a Quiet Time on a Maternity Ward: Engaging Patients and Staff to Assess Benefits and Barriers ''($ 12,295)
The 2015-2016 CARE competition is generously funded by St. Mary’s Hospital Foundation
St. Mary’s Hospital Center Featured in CBC’s Documentary “Keeping Canada Alive”
On May 6th, 2015, CBC TV dispatched over 60 camera crews to hospitals across Canada to capture on film, powerful stories of patients and health care providers over a single dramatic 24-hour day in the life of the Canadian health care system. The primetime documentary series called “Keeping Canada Alive”, features six one-hour TV episodes and one of the biggest online experiences – 24-hour website digital streaming footage (webisodes) that highlight 36 different emotionally-charged stories that happened in that single day in hospitals across Canada, including St Mary’s Hospital.
Click here to see the on-line footage of cataract surgery at St. Mary’s Hospital,
Keeping Canada Alive” premieres Sun., Oct. 4, 2015, at 9 p.m., on CBC. Check the website for more extras and details on the series.
Dr. Jane McCusker, a principal scientist at St Mary’s Research Centre, is leading a national research network to develop a new generation of self-management programs for Canadians living with multiple chronic illnesses.
Her pan-Canadian research team has just launched an online national survey to allow people with chronic illness and their caregivers to give their input into what the top priorities for research should be for self-management of multiple chronic diseases. If you are 18 or older and affected by chronic illness, you can complete the online survey here.
August 13, 2014
Autonomous Medicine for Space and near to home
Future human exploration of Space beyond Earth orbit and the Moon must deal with a reduced and even non-existent opportunity for the quick return of a sick or injured crew member back to Earth for medical treatment. These missions will also face considerably increased communications delays between the Crew Medical Officer (CMO) and the ground based Flight Surgeon (FS). At times, these communications will be impossible. Such isolation requires a change in medical support doctrine, from one of dependence on telemedicine to that of medical autonomy which can be achieved through a virtual medical crew member, a "doc-in-a-box", if you will and integrated crew training.
The reasoning part of the Doc-in-a-box, more properly referred to as the Advanced Crew Medical System (ACMS) in space exploration livery and Autonomous Medical System (AMS) for Earth applications, is based on current research being performed at St. Mary's Research Centre in Montreal. The goal of the research is to develop a computerized system capable of receiving examination information directly through interfaced sensors and indirectly through observations entered by a trained medical professional and, based on this examination information, establish a diagnosis and prescribe treatment.
The ACMS / AMS is comprised of two principal elements: a decision engine which processes the examination information based on rules and associations and a Clinical Knowledge Base which is derived from evidence-based medicine and combined with practice experience of physicians throughout the World.
Like human doctors, the ACMS / AMS needs to read and understand medical guidelines as they are the vehicle through which the medical knowledge, needed to stay current with advancements in clinical medicine, is disseminated. The application of machnie learning technology and natural language processing (NLP) in support of maintaining the system's medical currency are critical to the development of a truly autonomous system.
On Earth, the need for an AMS ia as acute as is the need for the ACMS in space, but manifests itself in a different form. Western medicine, as currently practiced, is expensive to the western economies and unaffordable to the developing ones. Evidence-baased health care applied systematically to every medical encounter throughout the whole World irrespective of the parctitioner's skill level can be provided at greatly reduced costs through the use of computers programmed for autonomous medicine.
For an update on the current state of this research and to view a video describing this concept, please click on the link.
April 23, 2014
The DUrAA (Départements d’Urgence Amis des Aînés) project has completed its first phase – a survey of elder-friendly care in Quebec emergency departments. In phase two, four emergency departments will be invited to participate in an in-depth study. The goal is to generate recommendations to improve elder-friendly care in emergency departments. For more information please see: (link to full document).
March 13, 2014
The DIRECT-sc team is pleased to announce that they have received continuation funding for their research program on depression self-care interventions for people with chronic conditions. This funding will support a Collaborative Community Research Component - a series of inter-related studies that will take place in collaboration with community programs that provide services to adults with chronic physical conditions, such as cancer, arthritis, or visual impairment. For more information please see: click here.
December 3, 2013
The FRQS in partnership with the Direction de l'organisation des services de première ligne (Ministère de la Sante et des Services sociaux du Québec) and Pfizer Canada Inc. launched a new knowledge network on primary health care and services, led by Jeannie Haggerty: Réseau-1 Quebec.
** Update - Visit the new website at http://reseau1quebec.ca/ **
November 25, 2013
The Health Experiences research team of St. Mary's is thrilled to announce the launch of their website www.healthexperiences.ca. The website features the results of the first module: Family Caregiving based on individual interviews with 39 Canadians. This provides an opportunity to see, hear, and read a range of experiences from people who care for someone with a chronic physical illness. The Health Experiences team, lead by Susan Law, will be launching a French version of the website in early 2014. Work is also in progress for two exciting new modules - experiences of breast cancer in women, and immigrant experiences with anxiety and depression.
June 28, 2012
National Post article highlights St. Mary's study
'Nudging doctors towards a paperless future'